FDR adjustments of Microarray Experiments (FDR-AME)
نویسندگان
چکیده
Purpose This R package adjusts p-values generated in multiple hypotheses testing of gene expression data obtained by a microarray experiment. The software applies multiple testing procedures that control the False Discovery Rate (FDR) criterion introduced by Benjamini and Hochberg (1995). It applies both theoretical-distribution-based and resampling-based multiple testing procedures, and presents as output adjusted p-values and p-value plots, as described in Reiner et al (2003). It goes beyond Reiner et al in offering adjustments according to the adaptive two stage FDR controlling procedures in Benjamini et al (2001, submitted), and in addressing differences in expression between many classes using one-way ANOVA.
منابع مشابه
A note on the false discovery rate and inconsistent comparisons between experiments
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